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CAN occurs when nerve damage affects the heart, which can be caused by prolonged high sugars

NO is then metabolized to the nitric oxide oxidation products nitrite and nitrate through a series of reactions involving O 2 and oxygen (Fig

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doi: 10.1017/S0950268806007096 [DOI] [PMC free article] [PubMed] [Google Scholar] [75].Shaffer L

Crit Rev Food Sci Nutr 58:924941 Gong L, Liao L, Dai X, Xue X, Peng C, Li Y (2021) The dual role of immune response in acetaminophen hepatotoxicity: implication for immune pharmacological targets

Moreover, activating GABA receptors or increasing GABA levels reduces symptoms of CIPN