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Professor of Neurology, Geffen School of Medicine at UCLA Director, UCLA Comprehensive Stroke Center UCLA Los Angeles, California Dr

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It supplies vitamin B12 and Zn: vitamin B12 maintains myelin sheath integrity (preventing prefrontal cortex damage), while zinc modulates TPH1 activityboth deficiencies are associated with higher depression risk (306, 307)

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Concurrently, lactate accumulation contributes to an acidic tumor microenvironment that impairs T cell effector function, induces exhaustion, and suppresses proliferation [83]