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Description

Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, et al

Formation and Mechanism Long-term UV exposure triggers melanin production to prevent sun damage Oxidative stress due to heat damages skin cells Appearance Face, hands, arms, neck, and feet Distinguishing Features Uneven tanning of the body (Appears only on the exposed areas Freckles or sun spots Often appears with aging Uneven Skin Tone In uneven skin tone, there are no defined dark spots, but general skin dullness or patchy pigmentation