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2nd Edn (Boca Raton: CRC Press), 24

Kinetic parameters were determined by fitting initial velocity data to the MichaelisMenten equation using Origin software (OriginLab) from technical replicate assays ( n = 3)

Mitochondria-targeted meganucleases Mitochondria-targeted meganucleases (mitoARCUS), derived from the naturally occurring I-CreI nucleic acid endonucleases, are small, highly specific single-component proteins