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While acute iron exposure produced minimal biochemical changes and did not sensitize cells to oxidative or ferroptotic challenges, chronic iron exposure induced ferritin upregulation, mitochondrial superoxide accumulation, suppression of GPX4 expression, elevated lipid peroxidation and loss of cellular glutathione (GSH)

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There are two F16 isomers that can specifically display mitochondria in the green and red channels, respectively, due to their unique fluorescence properties, providing new ways of studying mitochondrial targeting by F16

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In humans, ochratoxin A can have a severe immunosuppressive effect at low and high exposure doses

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