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In addition, IGF-1 LR3 may enhance tumor stem cell characteristics by inducing epithelial mesenchymal transition (EMT), leading to increased chemotherapy resistance and recurrence risk

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References suggest it as a tetrasubstituted variant of the shortest functional GHRH sequence, denoted GRF (1-29)

The folate content was 80% and 40% higher in the dough after fermentation and in the wholemeal rye bread, resp., compared to the starting flour, and similarly, 109% and 38%, resp., in the wheat bread