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Another important unanswered question concerns the pathophysiological interactions between astrocytes and other glial cells, such as microglia and oligodendrocytes, under neurodegenerative conditions and their associated microenvironments

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We quantified pathway activity for each cell and identified 29 metabolic pathways that were significantly over-dispersed across the different cell types

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It is common to see children affected by autism have a mutation of the MTHFR gene, which interferes with the body's ability to convert folate into methyl folate