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2021;5:e2001131

1 injection every 2 weeks should be taken to maintain the results

93,94,95,96 Advancements in carrier technology and nucleic acid modification techniques have led to significant progress in overcoming these challenges, as exemplified by the first siRNA drug, patisiran (Onpattro), which has been approved for treating hereditary transthyretin-mediated amyloidosis by degrading mRNA encoding transthyretin (TTR)

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Valcheva P, Cardus A, Panizo S, Parisi E, Bozic M, Lopez Novoa JM, Dusso A, Fernndez E, Valdivielso JM (2014) Lack of vitamin D receptor causes stress-induced premature senescence in vascular smooth muscle cells through enhanced local angiotensin-II signals

Storing it in the refrigerator door exposes it to temperature swings every time the door opens