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Clinicians and patients should therefore be aware that HbA1c is not always a reliable standalone marker when nutritional deficiencies or haematological conditions are present

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It has no established upper limit for toxicity at supplementation doses used in clinical practice (500 to 1,000 mcg per day)

[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Li W., Sigley J., Pieters M., Helms C.C., Nagaswami C., Weisel J.W., Guthold M