glutathione and napqi 5οΈβ£ Antidote: NAC (N-acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. π’ Example: Hospitals use NAC as the standard treatment for APAP overdose The metabolic pathways of acetaminophen
The metabolic pathways of acetaminophen (APAP) in the human body. The Download Scientific Diagram Acetaminophen metabolism. NAPQI, N acetyl p benzoquinone imine; CYP450, Download Scientific Diagram A crossomics analysis of acetaminopheninduced hepatotoxicity in rat liver Sumida 2015 Rapid Communications in Mass Spectrometry Wiley Online Library The conjugation of acetaminophen by glutathione and cytochrome P450. Download Scientific Diagram Pharmacology 401 k Paracetamol NAPQI Glutathione COX3 Poisoning Antidote AcetylCysteine YouTube glutathione napqi Metabolic pathway for NAPQI formation and detoxification by conjugation
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