glutathione synthetase deficiency smear Frontiers #imageoftheday, π A 24-year-old man
#imageoftheday, A 24 year old man develops acute jaundice and dark urine after starting trimethoprim sulfamethoxazole. A peripheral smear reveals the specific cellular defects shown. The underlying Inborn errors in the metabolism of glutathione Orphanet Journal of Rare Diseases Springer Nature Link Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation Scientific Reports Glutathione Synthetase Deficiency as a Cause of Hereditary Hemolytic Disease New England Journal of Medicine Hematological Diagnostics Springer Nature Link Glutathione synthetase deficiency MedLink Neurology
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