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Higher doses above 500 mcg are not recommended due to diminishing returns and increased side effect risk

Abstract APR-246 is a promising new therapeutic agent that targets p53 mutated proteins in myelodysplastic syndromes and in acute myeloid leukemia (AML)

Strzalkowski NDJ, Chau AD, Gan LS, Kiss ZHT

Because dietary supplements do not undergo the same pre-market approval process as prescription medications, product quality can vary widely

For instance, its important that all equipment used for reconstitution is sterilized prior to use and only sterile bottles should be utilized for storage purposes