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MRI with T1 and T2 mapping can detect copper deposition with greater sensitivity than ultrasound, though cost limits its use as a screening tool [7]

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Es ist wichtig zu beachten, dass die Konzentration nicht der einzige Wirksamkeitsfaktor ist: Die galenische Formulierung, der pH-Wert und das Vorhandensein von Cofaktoren beeinflussen die Bioverfgbarkeit des Peptids erheblich

4.1 Oxidative stress and mitochondrial damage Oxidative stress and subsequent mitochondrial damage are the key pathological initiating factors of toxicity-induced hepatic metabolic barrier damage

A good antioxidant should specifically quench free radicals, chelate redox metals, interact with other antioxidants within an antioxidant network, have a positive effect on gene expression, be readily absorbed, have a concentration in tissues and biofluids at a physiologically relevant level, act in both aqueous and/or membrane domains (2)

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