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With two inlet channels in a T-shaped mixer, each carrying a different liquid component, such as the ethanolic solution of the lipids and the low pH buffer solution with the nucleic acids, the chaotic and turbulent flow at the T-junction, where the two flows meet, facilitates rapid and thorough mixing of the two liquids and yielding lipid nanoparticles in the outlet (Jrgens et al., 2023

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