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Vargas R, Martinez-Martinez N, Lizano-Barrantes C et al (2025) Advancing through the blood-brain barrier: mechanisms, challenges and drug delivery strategies: review paper

However, this is not the same as proving long-term safety in humans

The start-up meeting took place in Barcelona, Spain in February 2017, followed by one meeting of the subgroup coordinators in Heidelberg, Germany in November 2017 and a face-to-face meeting for the whole guideline group in Athens, Greece in September 2018 (at the meeting of the Society for the Study of Inborn Errors of Metabolism (SSIEM))