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Theres a family history of early greying or autoimmune conditions like vitiligo

However, the recovery of these regenerative capabilities (by increased expression of NAMPT for example) change the physiology of the cells towards stem-like cells, gaining some cancer properties, such as unlimited proliferative capacity, altered metabolism, DNA-repair, methylation alterations, with phenotype similar to CSCs, which deregulation by any other mutation initiate the tumor

Int J Dev Neurosci 40:9296 Lillig CH, Holmgren A (2007) Thioredoxin and related moleculesfrom biology to health and disease

10.1007/s00436-001-0580-5 41

Gut Imbalances: Dysbiosis, intestinal permeability (leaky gut), and gut infections can disrupt thyroid function, trigger autoimmune reactions, and contribute to inflammation