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EGCG could target multiple pathways through different direct binding proteins [2]

PMID: 7977999

Sections were mounted with Canada Balsam and imaged using a Leica SP8 confocal microscope

In clinical practice, many patients begin noticing gradual changes within 8-12 weeks, while more pronounced skin-brightening effects may require 3-6 months of structured therapy

doi: 10.1038/s41467-020-18262-6 190 YaoY.CaiX.FeiW.YeY.ZhaoM.ZhengC

In the orally sensitized model, we observed increased mast cell infiltration and Th2 cell frequency in the intestine mucosa, despite the absence of concurrent rises in allergen-specific antibodies