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456,457 Anti-CTLA-4 antibodies are confined to trigger intracellular signal pathways, including cell cycle regulation pathways which do not overlap with anti-PD-1/PD-L1 antibodies

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Genetically predicted higher l-carnitine was associated with lower HDL-cholesterol in men (effect size 0.04, 95% CI 0.06 to 0.02), and not in women (0.004, 95% CI 0.05 to 0.06, p value=0.88)

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