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The high-dose (5 mg/ml) AR68 treatment groups total hair counts increased significantly to 4.421% (from 182.182 to 189.909 hairs/cm 2 ) after 24 weeks, whereas the placebo groups total hair counts decreased slightly at 24 weeks (from 181.714 to 181.524 hairs/cm 2 )

Feeding experiments not only confirmed the previously described ability of nitrate to promote NR activity 53 , they also demonstrated that elevated nitrate levels suppress GSNOR1 activity (Fig

GSTs modify a broad range of molecules including secondary metabolites and exogenous substrates, which are often referred to as xenobiotics, for their detoxification

Quantitative data were expressed as the mean and SD of triplicate determinations

Tabe, Y, Konopleva M, Tsao T, Lapillonne H, Jackson CE, Andreeff M