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Located at : License : CC BY-NC-SA: Attribution-NonCommercial-ShareAlike Dennert G, Zwahlen M, et al

Cystathionine -synthase (CBS) catalyzes the condensation of serine with Hcy in a pyridoxal-5-phosphate-dependent (PLP-dependent) manner, resulting in the formation of cystathionine

Whereas FAT10 is exclusively found in mammals, NUB1 variants are also present in flies and plants, suggesting a more conserved function that is potentially linked to the role of NUB1 in accelerating NEDD8 degradation 41