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AhpE is oxidized by peroxides to form a sulfenic acid intermediate (AhpE-SOH) that can be reduced directly by Mrx1

Finally, we discuss new challenges and opportunities for targeting ferroptosis as a potential strategy for treating ferroptosis-related diseases

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To elucidate the capability of GSH biosynthesis in these strains, resting cells were used for GSH synthesis

The discovery of lactylated PRLMs in 2019 further expanded this research area (Fig

However, in specific local areas depending on TAM subtype and activity, redox-active iron can still accumulate