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Ubiquitous protein lactylation in health and diseases

This can lead to cardiovascular disease, increasing the risk of heart attack and stroke

Although our collective findings pointed at excess oxidative stress in the cytosol of parkin-deficient brain (herein), these unbiased proteomic screens had previously identified dysregulated cytosolic as well as mitochondrial enzymes without apparent difference in mitochondrial structures (or numbers) within neurons of the nigrostriatal pathway [22, 36]

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In one study, more than 40% of patients treated with SSRIs reported sexual side effects

To accomplish this, intestinal cells are held together by a series of proteins called tight junctions