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SPF blocks the UV trigger, but it doesn't neutralise the melanin already queued up for production

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Exploring the association between obesity and cerebral inflammation after stroke, obese mice fed a high-fat (60%) diet showed larger post-stroke infarct volumes and increased chemokine expression (CXCL-1 and CCL3), blood-brain barrier (BBB) permeability, and neutrophil and microglia counts [86]