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This apparent contradiction in TAM behavior underscores the complexity of their role in the TME

The PCA of the nine adjusted metabolite concentration values (glutathione, glutamate, and glutamine in each of the three voxels, ACC, Insula, and Visual) resulted in three components with an eigenvalue greater than 1

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This mechanism is different from the previously suggested theory of increasing GSH levels

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Glutamic acid can also be synthesized from several different amino acids, including glutamine