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[8] Niacinamide Dietary requirements for niacin can be met by the ingestion of either nicotinic acid or nicotinamide

doi: 10.1016/j.jsbmb.2015.05.005

However, under pathological conditions, activated MMPs are associated with increased degradation of ECM components and are involved in ECM re-modeling (Dollery et al., 40 oligomers can increase MMP-2 activity in stimulated astrocytes and correlated with increased oxidative stress, inflammation and reduced cell viability