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A Role for Formaldehyde Detoxification in Bacterial Pathogenesis Evidence for Horizontal Transfer of nmlR-adhC-estD Genes Between Pathogenic Species The presence of inducible formaldehyde detoxification systems in non-methylotrophs, including those that cause human diseases, hints at the significance and role of this toxic aldehyde in bacterial physiology

Oxygen activation is often achieved by two mechanisms (Apel and Hirt, 2004): Absorbing excess energy sufficient to rotate the spin of one unpaired electron to make a single state ( 1 O 2 ), during which two electrons are of opposite spin

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FA-97 (caffeic acid phenethyl ester 4-O-glucoside) is a new synthetic CAPE derivative shown to attenuate body weight loss, colon length shortening, increased colonic inflammatory cell infiltration, and pro-inflammatory cytokine production (99)

Key patient characteristics and outcomes are presented in Table 1