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20,350 This phenomenon is evidenced by the significantly higher concentration of secondary BAs in the intestines and fecal samples of SPF mice compared to GF mice, providing strong evidence for their microbial origin

C.EttelM.et al (2019)

F.KireevR.TresguerresA

123 Sulfasalazine is clinically used for treating ulcerative colitis

10.1515/jbcpp-2018-0036 62 TianT.WangZ.ZhangJ

Its C-type Lectin domain can down-regulate NF-B and mitogen-activated protein kinase (MAPK) pathways and might thus interfere with DC and macrophage maturation and drive IL-10 release and Th2 skewing (102, 103)