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specifically, the entire loaves were cooled for 2 h, dried, and finely ground to obtain a representative homogeneous mixture of both crust and crumb before extraction

Intellia started dosing patients in their phase I/II trial in 2020

Transcription levels of target genes were quantified by the 2 CT method, normalization to the geometric mean of RPLP0 and RPLP2 as reference genes, as described previously 58