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Siebner AS, Griesbaum J, Huus KE, Flgge J, Hopfensperger K, Michel T, Schneiderhan-Marra N, et al

FcR-mediated functions control a broad array of antibody-driven therapeutic mechanisms, including complement-dependent cytotoxicity (CDC), antibody-dependent cell cytotoxicity (ADCC), antibody-dependent cell phagocytosis (ADCP), and the induction of cell death by apoptosis