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Additionally, ROS-mediated activation of p53 represses SLC7A11 transcription impairing cystine uptake via system Xc - and further diminishing GPX4 activity [17, 18] Mitochondria significantly contribute to ferroptosis via oxidative metabolism

10.1038/onc.2016.360 150 UbertiniV.NorelliG.D'ArcangeloD.GurtnerA.CesareoE.BaldariS.et al

Die prklinische Forschung zeigt konsistent: In Tiermodellen beschleunigte das Peptid die Heilung von Sehnen, Muskeln und Bndern, zeigte entzndungshemmende und schmerzlindernde Eigenschaften, schtzte den Magen-Darm-Trakt und wies ein gnstiges Toxizittsprofil auf