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3Ba), which emphasizes the dynamic shift in cellular composition over time, with increasing contributions from epithelial and stromal cells in PDTGs

Materials and Methods Reagents Ceramide standards and oleoyl-lysophosphatidate (LPA) were purchased from Avanti Polar Lipids (Alabaster, AL, USA)

In a study with type 2 diabetic rats treatment consisting of enalapril, menhaden oil or -lipoic acid as monotherapies or their combination were initiated 16 weeks after induction of hyperglycemia and treatment lasted 12 weeks (116)

Conjugated bile salts are more water-soluble and generally less toxic (51), whereas unconjugated forms, such as sodium cholate, tend to be more potent but are more toxic (46)