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Neurol Res Pract 6(1):30 Hopkins AL (2008) Network pharmacology: the next paradigm in drug discovery

RvD, resolvin D

J., Andrews, L

Barry Conrad Nochi, gnocchi, nochi

Armando I, Wang X, Villar VA, Jones JE, Asico LD, Escano C, Jose PA

The serine deprivation-dependent induction is regulated by the activating transcription factor 4 (ATF4) and can be reversed by the addition of glycine and serine, but not by other amino acids like leucine or cysteine ( 2.2 CHAC1 regulation through the ATF4-CHOP axis during ER stress The link between amino acid depletion and ATF4 directly connects to a major upstream regulator of CHAC1: the ER stress pathway