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220 Further study is required to determine sex-specific signaling pathway responses upon exercise

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SUPEROXIDE, HYDROGEN PEROXIDE, AND PEROXYNITRITE GENERATION Despite the fact that superoxide can be generated in extramitochondrial reactions, in most cell types mitochondria appear as the main source of superoxide generation

Furthermore, while the interaction between SOD activity and EGCG is not clearly established, it has been reported on rats with acetic acid-induced colitis an increases activity of SOD in EGCG-treated rats in comparison with placebo or control rats

Eischen CM, Kottke TJ, Martins LM, Basi GS, Tung JS, Earnshaw WC, Leibson PJ and Kaufmann SH