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Figure 1 Entry and Replication Spike protein (S protein) of coronavirus determines the viral entry into the host cells (de Wit et al., 2003b) and SARS-CoV-2 (Wu et al., 2020b) (Figure 1), dipeptidyl peptidase 4 for MERS-CoV (Raj et al., 2013), and CD209L for SARS-CoV [26]