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Antibiotic-induced gut dysbiosis leads to activation of microglia and impairment of cholinergic gamma oscillations in the hippocampus

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An umbrella meta-analysis published in the International Journal of Vitamins and Nutrition Research confirmed that L-carnitine supplementation can successfully manage reductions in weight, BMI, and waist circumference

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A similar scenario has in fact been reported recently in an alcoholic liver disease model in which long-term alcohol consumption activated NF-B in Kupffer cells, whereas NF-B activation in hepatocytes was inhibited 45

By addressing tissue-specific senescence and its relationship with local microenvironments, we can develop therapies that more effectively target aging in diverse tissues