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12 Meanwhile, computational design approaches are accelerating the development of PROTACs and AUTACs, enabling targeted degradation of disease-associated proteins through UPS or autophagy, respectively

demonstrated that treating Caco-2 cells (which structurally and functionally resemble differentiated small intestinal epithelial cells) with coffee bean extract(CBE)-treated fecal microbiota suppressed MRP4 expression, whereas CBE alone did not have this effect

2018 Nov 13;9(1):4630

Thin Solid Films 426:9499

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The heteroatom(s) O, N and S may be placed at any interior position of the heteroalkyl group or at the position at which the alkyl group is attached to the remainder of the molecule