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Video Lecture Media Attributions Receptor Location Casey Henley is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license Inactivated G-Protein Complex Casey Henley is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license Alpha Subunit Effects Casey Henley is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license Signal Amplification Casey Henley is licensed under a CC BY-NC-SA (Attribution NonCommercial ShareAlike) license

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Arutjunyan A, Kozina L, Stvolinskiy S, Bulygina Y, Mashkina A, Khavinson V (2012-04-06)

4 Clinical potential in cardiovascular and metabolic disorders Randomized and crossover trials report consistent BP reductions with beetroot juice or nitrate-matched foods, as well as improved endothelial function in patients with hypercholesterolemia and other at-risk groups

For serum samples, 75 L of chloroform:methanol extraction solvent (v:v = 1:2) was added to 20 L of mouse serum, with the exception of the serum from WT, Gclc L-KO, Nrf2 L-KO, and L-DKO mouse serum, for which 20 L of mouse serum was combined with 180 L of chloroform:methanol extraction solvent (v:v = 1:2) containing internal standards at the final concentrations: 5 nM D7-Sphinganine (Avanti Polar Lipids Inc., Cat# 860658), 12.5 nM D3-Deoxysphinganine (Avanti Polar Lipids Inc., Cat# 860474), and SPLASH LIPIDOMIX (1:1000, Avanti Polar Lipids Inc., Cat# 330707)