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doi: 10.1007/s12031-022-01999-8

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Beyond its primary function, iron is required also for thyroid hormone synthesis because the thyroperoxidase enzyme (TPO) needs to bind with a heme group to become active on the apical membrane of thyroid cells

This inhibition results in a reduced mitochondrial membrane potential and decreased ATP production

Metabolomic profiling of blood plasma in patients with primary brain tumours: basal plasma metabolites correlated with tumour grade and plasma biomarker analysis predicts feasibility of the successful statistical discrimination from healthy subjects - a preliminary study