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How your body uses melatonin: First, lets look at how much melatonin your body makes

Morioka S, Perry JS, Raymond MH, Medina CB, Zhu Y, Zhao L, et al

In all 5 variants, the C-terminal cysteine (C212), which forms a disulfide bridge with the C H 1 domain of the HC in the final assembled state, was mutated to a serine