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Their optimal pH for stability might differ slightly, and storing them together could lead to gradual degradation of one or both compounds, rendering your research invalid

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Hence, while the capacity of the bivalent vaccines in inducing VOC-specific nAbs and improving protective immunity to SARS-CoV-2 variants are still under investigation, it is possible that their capacity to induce immune mediated resistance to Omicron subvariants remains largely dependent on effector T cells