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In addition, cotreatment of docetaxel-resistant NSCLC with docetaxel plus R162 inhibited cancer cell growth and metastasis both in vitro and in xenograft mouse models, again suggesting that combination therapy with anticancer drugs plus a GLUD1 inhibitor is an effective cancer treatment 23

Dysregulation of this axis leads to ovarian dysfunction and abnormal estrogen secretion, which can directly impair fertility by altering the thickness and quality of the endometrium 196,212,213

Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes

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The patients hemoglobin improved with red blood cell transfusion and cessation of rasburicase

Isoflavones alter male and female fertility in different development windows