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To confirm this, we used siRNA to knockdown both of these genes and examined the effects on TNBC cell growth and migration

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Harrison DJ, Cantlay AM, Rae F, Lamb D, Smith CA: Frequency of glutathione S-transferase M1 deletion in smokers with emphysema and lung cancer

For example, pembrolizumab combined with cisplatin and pemetrexed showed an ORR of 86% and a 3-year OS of 71.9% in previously untreated metastatic non-squamous NSCLC (NCT02578680), illustrating the potential of immunotherapy-platinum combinations [100]