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Footnotes Peer review under responsibility of Transdisciplinary University, Bangalore

Additionally, 3-BrPA, a small-molecule glycolytic inhibitor that is selectively taken up through monocarboxylate transporter 1 (MCT1), has been shown to have strong antitumor effects in murine models by disrupting HK2-VDAC interactions and lowering mitochondrial hyperpolarization [89]

A Myers cocktail is an increasingly popular intravenous therapy

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Inefficacy of infliximab in primary Sjgrens syndrome: results of the randomized, controlled trial of remicade in primary Sjgrens syndrome (TRIPSS)

To shield cancer cells from therapeutic action, TAMs also secrete a variety of soluble factors into TME, such as interleukins, chemokines, etc