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used the Broad Institute gene response database The Connectivity Map to identify the top molecules capable of reversing gene expression characteristic for metastatic colon cancer

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J Am Acad Dermatol 67(4):630635 Kardaun SH, Sekula P, Valeyrie-Allanore L, Liss Y, Chu CY, Creamer D, Sidoroff A, Naldi L, Mockenhaupt M, Roujeau JC et al (2013) Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction

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The polypyrimidine tract, following the branch point and leading up to a conserved AG sequence at the introns end, aids in the recognition and proper alignment of the spliceosome to the 3SS, ensuring the intron is precisely cut and the exons are smoothly connected 32 (Fig

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