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Ochratoxin A mediates MAPK activation, modulates IL-2 and TNF-alpha mRNA expression and induces apoptosis by mitochondria-dependent and mitochondria-independent pathways in human H9 T cells

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A depressive phenotype was observed in the GS and GLT-1 cKO mice, correlated with increased levels of reactive oxygen/nitrogen species (ROS/RNS) within the mPFC, whereas a reduction in Glu-Gln concentrations was uniquely identified in the GS cKO mice