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It is important to take into consideration that many phytoconstituents have a low bioavailability when they are consumed orally as the body considered them xenobiotics (Kara et al., 2017) and, thus, may produce a significantly different result as that demonstrated from in vitro studies

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Nucleic acids research 32: 17921797

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Astrocytes exert robust antioxidant effects via the glutathione system and the glutamine, glutamate shuttle, both essential for maintaining neuronal mitochondrial function and ATP production