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Navarro-Trivino FJ, Ruiz-Villaverde R, Manuel Ramos-Pleguezuelos F, Vano-Galvan S

Furthermore, Lee and colleagues demonstrated that LUAD patients with NAA10 hypomethylation had decreased survival rates compared to those with NAA10 hypermethylation, underscoring its clinical value as a prognostic biomarker [128]

Superoxide dismutases (SODs) and catalase (CAT) are the major endogenous antioxidant defense systems against ROS (Racchi, 2013

Side Effects Allergic reactions (rash, swelling, breathing difficulties) Digestive issues (nausea, diarrhea) Hormonal imbalances (if overusing growth-related peptides) Increased blood sugar or blood pressure (with certain peptides like GHRPs) 2

2025;45:e12528

This burden is disproportionately heavier in low- and middle-income countries (LMICs), where underdiagnosis, limited therapeutic access, and healthcare disparities amplify disease impact (Payami et al., 2023