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The inflammatory nature of homocysteine and the effects of decreased myelin production before the occurrence of overt demyelination create a sustained low grade inflammatory response with a relative hyperexcitation of the peripheral and central nervous system

J Drug Deliv Sci Technol 90:105174

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[0530] In certain embodiments the transmembrane domain of the CAR can comprise or consist of the CD8a hinge domain

Gene 533:469476 Shao Q-h, Zhang X-l, Chen Y, Zhu C-G, Shi J-G, Yuan Y-h, Chen N-h (2018) Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways

In: Targeted Therapy in Cancer