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Furthermore, age-related changes in gastrointestinal function, such as decreased gastric acidity or alterations in intestinal motility, may further compromise B12 absorption

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doi: 10.1203/00006450-200201000-00014

Pharmacological FAS blockade might result in rapid changes in the lipid composition of the tumor cell membrane, which could impair a correct cellular localization of c-MET [33]