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Preferential Fat Oxidation

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Am J Biochem Biotechnol 4 : 167176 Morava E, van den Heuvel L, Hol F, de Vries MC, Hogeveen M, Rodenburg RJ, Smeitink JA 2006 Mitochondrial disease criteria: diagnostic applications in children

The initial 4-8 weeks are for building up a baseline level of pigmentation

In patients with a fatal outcome, a skin biopsy is recommended for the establishment of cultured fibroblasts, along with anticoagulated blood for DNA isolation/immortalization of lymphocytes and stored frozen aliquots of plasma, serum and urine [81]